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ZAK (Phospho-S165) polyclonal antibody

货号: BS64561

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS64561

Product Name :ZAK (Phospho-S165) polyclonal antibody

Swiss-Prot :Q9NYL2

Host :Rabbit

Reactivity :Human

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC:1:50~1:200

Background :This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ZAK (Phospho-S165) polyclonal antibody detects endogenous levels of ZAK protein only when phosphorylated at Ser165.

BiowMW :~ 91 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Mitogen-activated protein kinase kinase kinase MLT; Human cervical cancer suppressor gene 4 protein; HCCS-4; Leucine zipper- and sterile alpha motif-containing kinase; MLK-like mitogen-activated protein triple kinase; Mixed lineage kinase-related kinase; MLK-related kinase; MRK; Sterile alpha motif- and leucine zipper-containing kinase AZK; ZAK; MLTK; HCCS4

Immunogen :Synthetic phosphopeptide derived from human ZAK around the phosphorylation site of Serine 165.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of ZAK (Phospho-S165) polyclonal antibody at 1:500 dilution LaneA:SGC7901 whole cell lysate LaneB:HEK293T whole cell lysate LaneC:HCT116 whole cell lysate