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FOXO3 (Phospho-S315) polyclonal antibody

货号: BS64551

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS64551

Product Name :FOXO3 (Phospho-S315) polyclonal antibody

Swiss-Prot :O43524

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB:1:500~1:1000

Background :FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation.FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FOXO3 (Phospho-S315) polyclonal antibody detects endogenous levels of FOXO3 protein only when phosphorylated at Ser315.

BiowMW :~ 82, 97 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Insulin &Glucose Signaling,

Alternative Name :Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1; FOXO3A

Immunogen :Synthetic phosphopeptide derived from human FOXO3 around the phosphorylation site of Serine 315.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of FOXO3 (Phospho-S315) polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:NIH3T3 whole cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）