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hnRNP D0 (Phospho-S83) polyclonal antibody

货号: BS64534

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS64534

Product Name :hnRNP D0 (Phospho-S83) polyclonal antibody

Swiss-Prot :Q14103

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Background :hnRNP D/AUF1 binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3' untranslated regions of many protooncogenes and cytokine mRNAs. It also binds to double and single stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single stranded nonmonotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. It may be involved in translationally coupled mRNA turnover (referenced from swissprot).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :hnRNP D0 (Phospho-S83) polyclonal antibody detects endogenous levels of hnRNP D0 protein only when phosphorylated at Ser83.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; AU-rich element RNA-binding protein 1; AUF1; HNRPD; HNRNPD

Immunogen :Synthetic phosphopeptide derived from human hnRNP D0 around the phosphorylation site of Serine 83.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of hnRNP D0 (Phospho-S83) polyclonal antibody at 1:500 dilution LaneA:THP-1 whole cell lysate LaneB:SGC7901 whole cell lysate LaneC:The Lung tissue lysate of Mouse LaneD:The Lung tissue lysate of Rat