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Catenin delta 1 (Phospho-Y228) polyclonal antibody

货号: BS64524

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS64524

Product Name :Catenin delta 1 (Phospho-Y228) polyclonal antibody

Swiss-Prot :O60716

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC IF

Application_all :WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Background :The α, β, δ, and γ -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. δ-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding δ-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding δ-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. γ-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds α-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Catenin delta 1 (Phospho-Y228) polyclonal antibody detects endogenous levels of Catenin delta 1 protein only when phosphorylated at Tyr228.

BiowMW :~ 108 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :Catenin δ1; Catenin delta-1; Cadherin-associated Src substrate; Short name=CAS; p120 catenin; p120(ctn); p120(cas); CTNND1; KIAA0384

Immunogen :Synthetic phosphopeptide derived from human Catenin delta 1 around the phosphorylation site of Tyrosine 228.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of Catenin delta 1 (Phospho-Y228) polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate