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Cytokeratin 8 (Phospho-S432) polyclonal antibody

货号: BS64523

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS64523

Product Name :Cytokeratin 8 (Phospho-S432) polyclonal antibody

Swiss-Prot :P05787

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC IF

Application_all :WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Background :Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cytokeratin 8 (Phospho-S432) polyclonal antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at Ser432.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of Soluble Factors to EMT,

Alternative Name :Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; Short name=K8; Type-II keratin Kb8; KRT8; CYK8

Immunogen :Synthetic phosphopeptide derived from human Cytokeratin 8 around the phosphorylation site of Serine 432.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of Cytokeratin 8 (Phospho-S432) polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:A549 whole cell lysate LaneC:The Lung tissue lysate of Mouse LaneD:The Liver tissue lysate of Mouse LaneE:The Lung tissue lysate of Rat