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IL-6 polyclonal antibody（KU）

货号: BS6419

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS6419

Product Name :IL-6 polyclonal antibody（KU）

Swiss-Prot :P05231

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the brea own of fats and to improve insulin resistance.Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL-6 polyclonal antibody detects endogenous levels of IL-6 protein.

BiowMW :~ 23 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; B-cell stimulatory factor 2; BSF 2; BSF-2; BSF2; CDF; CTL differentiation factor; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HGF; HPGF; HSF; Hybridoma growth factor; Hybridoma growth factor Interferon beta-2; Hybridoma plasmacytoma growth factor; IFN-beta-2; IFNB2; IL 6; IL-6; IL6; IL6 protein; IL6; Interferon beta 2; Interferon beta-2; Interleukin 6 (interf

Immunogen :Recombinant full length Human IL-6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IL-6 polyclonal antibody at 1:500 dilution Lane1:HCC827 whole cell lysate(40ug) Lane2:PC3 whole cell lysate(40ug

Immunohistochemistry (IHC) analysis of IL-6 pAb in paraffin-embedded Rat Lung tissue.

HAO1 negatively regulates liver macrophage activation via the NF-κB pathway in alcohol-associated liver disease

JournalCELLULAR SIGNALLING

ApplicationWB

IF4.85

SpeciesMouse

PMID35953025
MiR-654-3p, reduced by the excessive ALKBH5, Alleviated the Inflammation in OA by targeting TNFRSF9, the trigger of the NF-κB pathway

JournalBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ApplicationWB

IF3.322

SpeciesHuman

PMID36228542
Beneficial Effects of Hordenine on a Model of Ulcerative Colitis

JournalMOLECULES

ApplicationWB

IF4.927

SpeciesMouse

PMID36985809
Therapeutic effects of shikonin on adjuvant-induced arthritis in rats and cellular inflammation, migration and invasion of rheumatoid fibroblast-like synoviocytes via blocking the activation of Wnt/β-catenin pathway

JournalPHYTOMEDICINE

ApplicationWB

IF6.656

SpeciesRat,Human

PMID37163904
A network pharmacology-based method to explore the therapeutic effect of honokiol on diabetes with comorbid depression in mice

JournalEUROPEAN JOURNAL OF PHARMACOLOGY

ApplicationIF,IHC

IF5

SpeciesMouse

PMID38754538