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ROS (phospho-Y2114) polyclonal antibody（KU）

货号: BS64028

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS64028

Product Name :ROS (phospho-Y2114) polyclonal antibody（KU）

Swiss-Prot :P08922

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B-lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occuring in many non-Hodgkin’s lymphomas. The c-ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-ROS (Y2114) polyclonal antibody detects endogenous levels of human ROS only when phosphorylated at Tyr2114.

BiowMW :~ 55-80 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :ErbB HER Signaling,

Alternative Name :Proto-oncogene tyrosine-protein kinase ROS; Proto-oncogene c-Ros; Proto-oncogene c-Ros-1; Receptor tyrosine kinase c-ros oncogene 1; c-Ros receptor tyrosine kinase; ROS1; MCF3; ROS

Immunogen :Synthetic phosphopeptide derived from human ROS around the phosphorylation site of Tyrosine 2114.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-ROS（Y2114) pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:The Brain tissue lysate of Mouse(40ug) Lane4:The Brain tissue lysate of Rat(40ug) Lane5:HEK293T whole cell lysate(40ug) Lane6:A549 whole cell lysate(40ug)