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C/EBP α (phospho-S193) polyclonal antibody

货号: BS64010

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS64010

Product Name :C/EBP α (phospho-S193) polyclonal antibody

Swiss-Prot :P53566/P05554

Host :Rabbit

Reactivity :Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α is a basic region/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP α uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growtharrested cells. In the liver, C/EBP α is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C/EBP α mRNA and protein, but also the DNA-binding activity of C/EBP α. C/EBP α functions as an important transcription factor that regulates different genes, including Prolactin gene expression.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-C/EBP α (S193) polyclonal antibody detects endogenous levels of C/EBP α protein only when phosphorylated at Ser193 (Mouse or Rat).

BiowMW :~ 37 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CCAAT/enhancer-binding protein alpha; C/EBP alpha; CEBPA; C/EBP α; C/EBPα

Immunogen :Synthetic phosphopeptide derived from mouse C/EBP α around the phosphorylation site of Serine 193.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-C/EBP α (S193) polyclonal antibody at 1:500 dilution Lane2:Raw264.7 cell lysate treated with PMA(100nM,15mins) Lane3:H9C2 ccell lysate treated with PMA(100nM,15mins)