产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Phospho-DNMT1-pS714 polyclonal antibody

货号: BS6347

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6347

Product Name :Phospho-DNMT1-pS714 polyclonal antibody

Swiss-Prot :P26358

Host :Rabbit

Reactivity :Human

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

Background :This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Phosphorylated Antibodies

BiowMW :Refer to Figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT;m.HsaI;DNMT1

Immunogen :A synthetic phosphorylated peptide around S714 of human Phospho-DNMT1-pS714(NP_001370.1).

Conjugate :Unconjugated

Modification :Phosphorylated

Immunofluorescence analysis of MCF-7 cells using Phospho-DNMT1-pS714 antibody . Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）