Product Name :Phospho-Bad-S112 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB,1:500 - 1:2000
Background :The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Phosphorylated Antibodies
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BAD;BBC2;BCL2L8;Bad
Immunogen :A synthetic phosphorylated peptide around S112 of mouse Bad(NP_031548.1?).
Modification :Phosphorylated
