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FTO polyclonal antibody

货号: BS62603

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62603

Product Name :FTO polyclonal antibody

Swiss-Prot :Q9C0B1

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FTO polyclonal antibody detects endogenous levels of FTO protein.

BiowMW :~ 58 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO;mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO; KIAA1752

Immunogen :Synthetic peptide, corresponding to Human FTO.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of FTO polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate(40ug) LaneB:Hela whole cell lysate(40ug) LaneC:A549 whole cell lysate(40ug) LaneD:The rat lung lysate of Mouse(40ug) LaneE:The rat kindey lysate of Mouse(40ug)