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SAP49 polyclonal antibody

货号: BS62486

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS62486

Product Name :SAP49 polyclonal antibody

Swiss-Prot :Q15427

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC:1:50~1:200

Background :SF3B4 is part of the SF3b complex which associates with the U2 snRNP component of the spliceosome and is essential for spliceosome assembly. SF3B4 can associate with BMPR-1A to inhibit BMP-mediated cell differentiation. Haploinsufficiency of SF3B4 has been described in Nager syndrome, a disease of craniofacial malformation condition. Increased copy number of SF3B4 has been shown to play a role in hepatocellular carcinoma progression.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SAP49 polyclonal antibody detects endogenous levels of SAP49 protein.

BiowMW :~ 49 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Splicing factor 3B subunit 4; Pre-mRNA-splicing factor SF3b 49 kDa subunit; Spliceosome-associated protein 49; SAP 49; SF3B4; SAP49

Immunogen :Synthetic peptide, corresponding to Human SAP49.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SAP49 polyclonal antibody at 1:500 dilution LaneA:L02 whole cell lysate LaneB:A549 whole cell lysate LaneC:HEK293T whole cell lysate LaneD:CT26 whole cell lysate LaneE:PC12 whole cell lysate