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RGS14 polyclonal antibody

货号: BS62458

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS62458

Product Name :RGS14 polyclonal antibody

Swiss-Prot :O43566

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC:1:50~1:200

Background :RGS domains bind directly to activated Ga subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Ga-GTP and Gbg. RGS proteins shorten the lifetime of the activated G protein. Western blot analysis shows strong expression of RGS14 as a primarily cytosolic protein restricted to brain and spleen. It is suggested that RGS14 may constitute a bridging molecule that allows cross-regulation of signaling pathways downstream from G protein-coupled receptors.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity :RGS14 polyclonal antibody detects endogenous levels of RGS14 protein.

BiowMW :~ 61 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Regulator of G-protein signaling 14

Immunogen :Synthetic peptide, corresponding to Human RGS14.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of RGS14 polyclonal antibody at 1:500 dilution LaneA:LOVO whole cell lysate LaneB:BV2 whole cell lysate LaneC:PC12 whole cell lysate