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PDK1 polyclonal antibody

货号: BS62449

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62449

Product Name :PDK1 polyclonal antibody

Swiss-Prot :Q15118

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB:1:500~1:1000

Background :Mitochondrial pyruvate dehydrogenase (PDH) catalyzes the oxidative decarboxylation of pyruvate and plays a central role in the regulation of homeostasis of carbohydrate fuels in mammals. PDH activity is controlled by a phosphorylation/dephosphorylation cycle, phosphorylation leading to inactivation and dephosphorylation leading to reactivation of PDH. The phosphorylation of PDH is catalyzed by pyruvate dehydrogenase kinase (PDK), the activity of which is stimulated by the products of PDH catalysis. PDK1 consists of alpha and beta subunits; the kinase activity resides in the alpha subunit. Three PDK isoenzymes have been identified in humans (PDK1, 2 and 3) and two have been identified in rodent (PDK1 and 2).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity :PDK1 polyclonal antibody detects endogenous levels of PDK1 protein.

BiowMW :~ 49 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Warburg Effect,AMPK Signaling Pathway,

Alternative Name :PDH kinase 1; PDK1; PDHK1

Immunogen :Synthetic peptide, corresponding to Human PDK1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PDK1 polyclonal antibody at 1:500 dilution LaneA:H1792 whole cell lysate LaneB:CT-26 whole cell lysate