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MYPT3 polyclonal antibody

货号: BS62438

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS62438

Product Name :MYPT3 polyclonal antibody

Swiss-Prot :Q96I34

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC:1:50~1:200

Background :The members of the MYPT family, MYPT1, MYPT2 and MYPT3 are the myosinbinding subunits of myosin phosphatase and an integral component of the myosin protein phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. MYPT1 is localized on stress fibers and is distributed close to the cell membrane and at cell-cell contacts to regulate myosin phosphatase activity. In addition to MYPT1, a novel isoform of MYPT1, MYPT2, also interacts with PPlc. MYPT3, also designated PP16A, inhibits protein phosphatase activity involving phosphorylase, myosin light chain and myosin substrates. It acts as a lipid anchor and binds PP1. MYPT3 localizes primarily to the cell membrane.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity :MYPT3 polyclonal antibody detects endogenous levels of MYPT3 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein phosphatase 1 regulatory subunit 16A; Myosin phosphatase-targeting subunit 3; PPP1R16A; MYPT3

Immunogen :Synthetic peptide, corresponding to Human MYPT3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MYPT3 polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate LaneB:A2780 whole cell lysate LaneC:HCT116 whole cell lysate LaneD:H9C2 whole cell lysate LaneE:CT-26 whole cell lysate