产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Nectin 4 polyclonal antibody

货号: BS62424

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62424

Product Name :Nectin 4 polyclonal antibody

Swiss-Prot :Q96NY8

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB:1:500~1:1000

Background :Nectin-4/Poliovirus Receptor-Like 4 (PVRL4) is a type-I transmembrane glycoprotein that belongs to the immunoglobulin superfamily and promotes cell-cell adhesion by serving as a major component of adherens junctions. The extracellular domain of Nectin-4, which contains an Ig variable-like domain (V) and two Ig constant-like domains (C), mediates binding to the measles virus and to neighboring cells through trans heterophilic interactions with Nectin-1. Unlike other nectin family members, which are widely expressed in adult tissues, Nectin-4 expression in humans is largely restricted to the placenta. Research studies have demostrated that Nectin-4 is overexpressed in a variety of human solid tumors of the pancreas, breast, lung, and ovary. Due to its restricted expression pattern in normal human tissues, Nectin-4 may serve as a novel diagnostic and therapeutic target for a variety of human tumors.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -21°C long term. Avoid freeze-thaw cycles.

Specificity :Nectin 4 polyclonal antibody detects endogenous levels of Nectin 4 protein.

BiowMW :~ 66 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Nectin-4; Ig superfamily receptor LNIR; Nectin cell adhesion molecule 4; Poliovirus receptor-related protein 4; Processed poliovirus receptor-related protein 4; NECTIN4; LNIR; PRR4; PVRL4

Immunogen :Synthetic peptide, corresponding to Human Nectin 4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Nectin 4 polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:MCF-7 whole cell lysate LaneC:PC12 whole cell lysate