产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

NRBF2 polyclonal antibody

货号: BS62416

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62416

Product Name :NRBF2 polyclonal antibody

Swiss-Prot :Q96F24

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB

Application_all :WB:1:500~1:1000

Background :Nuclear hormone receptors function as transcriptional activators when their cognate ligands are bound. Binding of the appropriate ligand induces a conformational change in the nuclear receptor, allowing it to interact with transcriptional coactivators. NRBF2 (Nuclear receptor-binding factor 2), also known as COPR (Comodulator of PPAR and RXR), is thought to act as a transcriptional coactivator by altering the activity of target nuclear receptors. Highly expressed in the liver, placenta and keratinocytes, NRBF2 can interact with at least 7 nuclear receptors including PPARα, PPARδ and PPARγ. In the presence of a bound ligand, NRBF2 can interact with nuclear receptors RARα, RARγ. and RXRα. NRBF2, which exists as two isoforms due to alternative splicing, is localized to both the nucleus and the cytoplasm.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NRBF2 polyclonal antibody detects endogenous levels of NRBF2 protein.

BiowMW :~ 40,34,26 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Nuclear Receptor Signaling,

Alternative Name :Nuclear receptor-binding factor 2; NRBF-2; Comodulator of PPAR and RXR; NRBF2; COPR

Immunogen :Synthetic peptide, corresponding to Human NRBF2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of NRBF2 polyclonal antibody at 1:500 dilution LaneA:HepG2 whole cell lysate LaneB:L02 whole cell lysate LaneC:Aml-12 whole cell lysate LaneD:PC12 whole cell lysate LaneE:C6 whole cell lysate