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NKX2-4 polyclonal antibody

货号: BS62392

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62392

Product Name :NKX2-4 polyclonal antibody

Swiss-Prot :Q9H2Z4

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB

Application_all :WB:1:500~1:1000

Background :TTF-1 (thyroid transcription factor-1, BCH, BHC, NK-2, Nkx2.1, Nkx2A, TEBP, TTF1) is a member of the Nkx2 family of homeodomain-containing transcription factors and regulates the transcriptional activity of thyroid-specific genes. TTF-1 influences organogenisis and the maintenance of the differentiated phenotypes of various tissues including thyroid, lung and brain. TTF-1, which is present in the epithelium of the lung, regulates transcription of the surfactant proteins (SP) A, B and C and is essential for lung morphogenesis. In the thyroid, TTF-1 elevates the expression of thyroid specific markers, thyroglobulin, thyroperoxidase and thyrotropin receptors. TTF-1 interacts with SRC-1 and CBP in vitro.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NKX2-4 polyclonal antibody detects endogenous levels of NKX2-4 protein.

BiowMW :~ 36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Homeobox protein Nkx-2.4; Homeobox protein NK-2 homolog D; NKX2-4; NKX2D

Immunogen :Synthetic peptide, corresponding to Human NKX2-4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of NKX2-4 polyclonal antibody at 1:500 dilution LaneA:MCF-7 whole cell lysate LaneB:H1792 whole cell lysate LaneC:PC12 whole cell lysate LaneD:CT-26 whole cell lysate