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MSX2 polyclonal antibody

货号: BS62390

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS62390

Product Name :MSX2 polyclonal antibody

Swiss-Prot :P35548

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC:1:50~1:200

Background :Msx homeobox genes encode for transcription factors that control morphogenesis and are expressed at sites of epithelial-mesenchymal interaction during embryogenesis, such as the Tooth. Two of these genes, Msx-1 and Msx-2, are key factors for the development of tooth and craniofacial skeleton. Msx-1 also down-regulates a master gene of skeletal cells differentiation. Msx-1 and Msx-2 contribute to the initial patterning of dentition as well as playing a pivotal role in terminal cell differentiation. In addition, Msx-1 and Msx-2 are expressed in the epidermis, hair follicles and fibroblasts of the developing fetal skin. In adult skin, Msx-1 and Msx-2 expression is confined to epithelially derived structures. Msx-2 is detected as a diffuse cytoplasmic signal in fetal epidermis and portions of the hair follicle and dermis, but is localized to the nucleus in the adult epidermis. Msx-1 and Msx-2 are also expressed during critical developmental stages of neural tube and neuralcrest, suggesting that these genes play an important role in organogenesis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MSX2 polyclonal antibody detects endogenous levels of MSX2 protein.

BiowMW :~ 34 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Homeobox protein MSX-2; Homeobox protein Hox-8; MSX2; HOX8

Immunogen :Synthetic peptide, corresponding to Human MSX2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MSX2 polyclonal antibody at 1:500 dilution LaneA:A549 whole cell lysate LaneB:HEK293T whole cell lysate LaneC:MEF whole cell lysate LaneD:H9C2 whole cell lysate

The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats

JournalJournal of Diabetes Research

ApplicationIHC

IF3.04

SpeciesRat

PMID29464183