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GNL3L polyclonal antibody

货号: BS62387

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS62387

Product Name :GNL3L polyclonal antibody

Swiss-Prot :Q9NVN8

Host :Rabbit

Reactivity :Human

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC:1:50~1:200

Background :Guanine nucleotide-binding protein-like 3-like protein, stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GNL3L polyclonal antibody detects endogenous levels of GNL3L protein.

BiowMW :~ 72 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Guanine nucleotide-binding protein-like 3-like protein; GNL3L

Immunogen :Synthetic peptide, corresponding to Human GNL3L.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of GNL3L polyclonal antibody at 1:500 dilution LaneA:H1792 whole cell lysate LaneB:MCF-7 whole cell lysate

免疫沉淀（IP）