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GDF7 polyclonal antibody

货号: BS62385

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS62385

Product Name :GDF7 polyclonal antibody

Swiss-Prot :Q7Z4P5

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB:1:500~1:1000

Background :Growth/differentiation factors (GDFs) are members of the TGF superfamily. Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis. GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development. Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members. GDF-3 is detectable in bone marrow, spleen, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary. GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs. GDF-6 and GDF-7 are closely related to GDF-5. GDF-8 has been shown to be a negative regulator of skeletal muscle mass.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GDF7 polyclonal antibody detects endogenous levels of GDF7 protein.

BiowMW :~ 47 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Growth/differentiation factor 7; GDF-7; GDF7

Immunogen :Synthetic peptide, corresponding to Human GDF7.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of GDF7 polyclonal antibody at 1:500 dilution LaneA:HCT116 whole cell lysate LaneB:HepG2 whole cell lysate

免疫沉淀（IP）