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FAIM2 polyclonal antibody

货号: BS62375

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62375

Product Name :FAIM2 polyclonal antibody

Swiss-Prot :Q9BWQ8

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB:1:500~1:1000

Background :FAIM2 (fas apoptotic inhibitory molecule 2), also known as LFG (protein lifeguard), TMBIM2 (transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death. Though mechanistically related to the Fas signal, FAIM2 does not protect cells from apoptosis that is mediated by TNF-α signaling. FAIM2 specifically regulates apoptosis by binding to the FAS receptor.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FAIM2 polyclonal antibody detects endogenous levels of FAIM2 protein.

BiowMW :~ 36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2; FAIM2; KIAA0950; LFG; LFG2; NMP35; TMBIM2

Immunogen :Synthetic peptide, corresponding to Human FAIM2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of FAIM2 polyclonal antibody at 1:500 dilution LaneA:BV2 whole cell lysate LaneB:U-87MG whole cell lysate LaneC:HEK293T whole cell lysate