产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

ELP2 polyclonal antibody

货号: BS62368

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62368

Product Name :ELP2 polyclonal antibody

Swiss-Prot :Q6IA86

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB:1:500~1:1000

Background :One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain. A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions. StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate. Because StIP1 can associate with several other members of the Stat family, it may serve a broad role in cytokine-signaling events.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ELP2 polyclonal antibody detects endogenous levels of ELP2 protein.

BiowMW :~ 100 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Elongator complex protein 2; ELP2; SHINC-2; STAT3-interacting protein 1; StIP1; ELP2; STATIP1

Immunogen :Synthetic peptide, corresponding to Human ELP2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ELP2 polyclonal antibody at 1:500 dilution LaneA:L02 whole cell lysate LaneB:HEK293T whole cell lysate LaneC:A549 whole cell lysate