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IARS2 polyclonal antibody

货号: BS62299
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS62299
Product Name :IARS2 polyclonal antibody
Swiss-Prot :Q9NSE4
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB IHC IF
Application_all :WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200
Background :The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Accurate discrimination of the structurally similar amino acids valine and isoleucine by isoleucyl-tRNA synthetase (IleRS) results, in part, from a hydrolytic editing reaction, which prevents misactivated valine from being stably joined to tRNAIle. IleRS joins Ile to tRNA(Ile) at its synthetic active site and hydrolyzes incorrectly acylated amino acids at its editing active site. A member of the aminoacyl-tRNA synthetase family, human IleRS has been identified as a target of antibodies in the autoimmune disease polymyositis.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :IARS2 polyclonal antibody detects endogenous levels of IARS2 protein.
BiowMW :~ 114 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Isoleucine--tRNA ligase, mitochondrial; Isoleucyl-tRNA synthetase; IleRS; IleRS
Immunogen :Synthetic peptide, corresponding to Human IARS2.
Conjugate :Unconjugated
Modification :Unmodification
Western blot (WB) analysis of IARS2 polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate LaneB:Hela whole cell lysate LaneC:H446 whole cell lysate LaneD:The Kidney tissue lysate of Mouse LaneE:The Testis tissue lysate of Mouse LaneF:The Kidney tissue lysate of Rat LaneG:The Testis tissue lysate of Rat

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com