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Maspin polyclonal antibody

货号: BS6215

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS6215

Product Name :Maspin polyclonal antibody

Swiss-Prot :P36952

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background :Maspin is structurally a serine protease inhibitor (serpin) that was initially isolated from normal human mammary epithelial cells. Serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases. Serpins control activated proteinases and several are involved in the regulation of cell death. Maspin is found in the extracellular matrix and at the plasma membrane. Maspin has been shown to act at the cell surface to block cell motility and inhibit invasion of breast and prostate cancer cells. Maspin is present in normal mammary epithelial cells but is absent in many tumor cell lines, yet no major structural alterations of the Maspin gene have been identified in tumor cells. Similarly, Maspin is expressed in normal prostate cells and downregulated or absent in prostate tumor cells..

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Maspin polyclonal antibody detects endogenous levels of Maspin protein.

BiowMW :~ 42 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Serpin B5; Maspin; Peptidase inhibitor 5; PI-5; SERPINB5; PI5

Immunogen :Recombinant full length Human Maspin.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of Maspin polyclonal antibody in extracts from HT-29 and NIH3T3 cells.

Immunohistochemistry (IHC) analysis of Maspin pAb in paraffin-embedded Human Colon tissue.

免疫沉淀（IP）

免疫组织化学（IHC）