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STXBP1 polyclonal antibody

货号: BS62093

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS62093

Product Name :STXBP1 polyclonal antibody

Swiss-Prot :P61764

Host :Rabbit

Reactivity :Human,Mouse,Rabbit

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Munc18-1 belongs to the Munc18 protein family that also includes Munc18-2 and Munc18-3. These proteins are highly conserved at the amino acid sequence level and play a critical role in membrane fusion. Munc18 proteins control SNARE complex formation and interact with syntaxin. In Munc18-1 knockout mice, neurotransmitter release is completely abolished. In addition, Munc18-1 acts as a molecular chaperone for syntaxin-1, allowing for formation of the SNARE complex at the plasma membrane. Munc18-1 also acts as a regulator of vesicle docking during exocytosis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :STXBP1 polyclonal antibody detects endogenous levels of STXBP1 protein.

BiowMW :~ 70kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Vesicle Trafficking presynaptic signaling,

Alternative Name :Syntaxin-binding protein 1; MUNC18-1; N-Sec1; N-Sec1;Protein unc-18 homolog 1; Unc18-1; Protein unc-18 homolog A; Unc-18A; p67; STXBP1; UNC18A

Immunogen :Synthetic peptide, corresponding to Human STXBP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of STXBP1 polyclonal antibody at 1:500 dilution Lane1:U-87MG whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:SHSY5Y whole cell lysate(40ug) Lane4:K562 whole cell lysate(40ug) Lane5:RAW264.7 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Mouse(40ug) Lane7:The Brain tissue lysate of Rat(40ug)