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PTK2 polyclonal antibody

货号: BS61896

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61896

Product Name :PTK2 polyclonal antibody

Swiss-Prot :Q05397

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Focal adhesion kinase was initially identified as a major 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src-encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase whose sequence and structural organization are unique as compared to other proteins described to date. Localization of p125 by immunofluorescence suggests that it is primarily found in cellular focal adhesions leading to its designation as focal adhesion kinase (FAK). FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles.

Specificity :PTK2 polyclonal antibody detects endogenous levels of PTK2 protein.

BiowMW :~ 125 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Actin Dynamics,Tumor Angiogenesis,Contribution of ECM and Cytoskeletal Factors to EMT,G Protein-coupled Receptors Signaling to MAPK Erk,

Alternative Name :Complement C1s subcomponent; C1 esterase; Complement component 1 subcomponent s; Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain; C1S

Immunogen :Synthetic peptide, corresponding to amino acids 407-467 of Human C1s HC.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PTK2 polyclonal antibody at 1:500 dilution Lane1:SK-OVCAR3 whole cell lysate(40µg) Lane2:LOVO whole cell lysate(40µg) Lane3:Beas-2B whole cell lysate(40µg) Lane4:A549 whole cell lysate(40µg) Lane5:PC3 whole cell lysate(40µg) Lane6:3T3-L1 whole cell lysate(40µg) Lane7:CT-26 whole cell lysate(40µg)