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CEP170 polyclonal antibody

货号: BS61661

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61661

Product Name :CEP170 polyclonal antibody

Swiss-Prot :Q5SW79

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Centrosomal protein 170kDa, also known as CEP170, is a protein that in humans is encoded by the CEP170 geneThe product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with the intraflagellar transport protein 81 (IFT81), the SH3-domain containing protein PRAX-1, and is phosphorylated by cyclin dependent kinase 1 (Cdk1) and polo-like kinase 1 (PLK1), and functions in maintaining Microtubule organization, cell morphology and cilium stability.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CEP170 polyclonal antibody detects endogenous levels of CEP170 protein.

BiowMW :~ 175 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Centrosomal protein of 170 kDa; Cep170; KARP-1-binding protein; KARP1-binding protein; CEP170; FAM68A; KAB; KIAA0470

Immunogen :Synthetic peptide, corresponding Human CEP170.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CEP170 polyclonal antibody at 1:500 dilution Lane1:L02 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug)