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SAR1B polyclonal antibody

货号: BS61634

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61634

Product Name :SAR1B polyclonal antibody

Swiss-Prot :Q9Y6B6

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :There are a number of components involved in the secretory pathway of cells. Vesicular traffic within the early secretory pathway is mediated by COPI- and COPII-coated vesicles. The COPII vesicle coat protein promotes the formation of endoplasmic reticulum (ER) derived transport vesicles that carry secretory proteins to the Golgi complex. The SAR1 gene encodes two isoforms, Sar1a and Sar1B, in mammalian cells. These proteins are low-molecular-weight GTPases, which are essential for the formation of transport vesicles from the ER. Mutations in the SAR1 gene result in Anderson’s disease (and/or chylomicron retention disease CMRD), a rare, autosomal recessive lipid malabsorption disorder characterized by chronic diarrhea, failure to thrive and hypocholesterolemia in childhood.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SAR1B polyclonal antibody detects endogenous levels of SAR1B protein.

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GTP-binding protein B; GTBPB; GTP-binding protein SAR1b; SAR1B; SARA2, SARB

Immunogen :Synthetic peptide, corresponding Human SAR1B.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SAR1B polyclonal antibody at 1:500 dilution Lane1:The Brain tissue lysate of Mouse(40ug) Lane2:The Brain tissue lysate of Rat(40ug) Lane3:HepG2 whole cell lysate(40ug) Lane4:HCT116 whole cell lysate(40ug)