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CDC23 polyclonal antibody

货号: BS61596

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61596

Product Name :CDC23 polyclonal antibody

Swiss-Prot :Q9UJX2

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 101% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CDC23 polyclonal antibody detects endogenous levels of CDC23 protein.

BiowMW :~ 75 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cell division cycle protein 23 homolog; Anaphase-promoting complex subunit 8; APC8; Cyclosome subunit 8

Immunogen :Synthetic peptide, corresponding to amino acids 267-311 of Human CDC23.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CDC23 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:THP-1 whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:RAW264.7 whole cell lysate(40ug)