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CADM3 polyclonal antibody

货号: BS61572

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61572

Product Name :CADM3 polyclonal antibody

Swiss-Prot :Q8N126

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Immunoglobulin superfamily member 4B (Cell adhesion molecule 3, Nectinlike protein 1) is a nectin family gene product that contains 2 Ig-like C2-type (immunoglobulin-like) domains and an Ig-like V-type (immunoglobulin-like) domain. IGSF4B is a single-pass type I membrane protein that localizes to cellcell interacting sites along the plasma membrane. IGSF4B functions as a cell adhesion molecule at cell-cell junctions. IGSF4B can be found as a homodimer and has a dual calcium-independent adhesion function; a homophilic cell-cell interaction and a heterophilic cell-cell interaction involving IGSF4, Nectin 1 and Nectin 3. IGSF4B may also interact with EPB41L1 which has a potential for regulating structure or function of cell-cell junctions by similarity. Isoform 1 is expressed in adult and fetal brain. Isoform 2 is highly expressed in the cerebellum but is also weakly expressed in placenta. IGSF4B has been found to be markedly over-expressed in glioma cell lines and prostate cancer cell lines.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CADM3 polyclonal antibody detects endogenous levels of CADM3 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cell adhesion molecule 3; Brain immunoglobulin receptor; Immunoglobulin superfamily member 4B; IgSF4B; Nectin-like protein 1; NECL-1; Synaptic cell adhesion molecule 3; SynCAM3; TSLC1-like protein 1; TSLL1

Immunogen :Synthetic peptide, corresponding to amino acids 144-188 of Human CADM3

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CADM3 polyclonal antibody at 1:500 dilution Lane1:HCT116 whole cell lysate(40ug) Lane2:HCC827 whole cell lysate(40ug) Lane3:PC3 whole cell lysate(40ug) Lane4:The Brain tissue lysate of Mouse(40ug) Lane5:The Brain tissue lysate of Rat(40ug) Lane6:The fetal Brain tissue lysate of Mouse(40ug) Lane7:The fetal Brain tissue lysate of Rat(40ug)