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PRPF19 polyclonal antibody

货号: BS61565

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61565

Product Name :PRPF19 polyclonal antibody

Swiss-Prot :Q9UMS4

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The spliceosome, the gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and 5 RNA molecules (U1, U2, U4, U5 and U6). Pre-mRNA splicing is essential to remove internal non-coding regions of pre-mRNA (introns) and to join the remaining segments (exons) into mRNA before translation. The PRP19-associated complex is required for stable association of U5 and U6 with the spliceosome after U4 is released. Changes within the spliceosome upon binding of the PRP19-associated complex include remodeling of the U6/5' splice site interaction and destabilization of Lsm proteins to allow further interaction of U6 with the intron sequence.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PRPF19 polyclonal antibody detects endogenous levels of PRPF19 protein.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Pre-mRNA-processing factor 19; Nuclear matrix protein 200; PRP19/PSO4 homolog; hPso4; Senescence evasion factor

Immunogen :Synthetic peptide, corresponding to amino acids 165-209 of Human PRPF19

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PRPF19 polyclonal antibody at 1:500 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:HCT116 whole cell lysate(40ug) Lane3:The Kidney lysate of Rat(40ug) Lane4:The Heart lysate of Mouse(40ug) Lane5:The Liver lysate of Mouse(40ug)