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CIDEB polyclonal antibody

货号: BS61564

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS61564

Product Name :CIDEB polyclonal antibody

Swiss-Prot :Q9UHD4

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The DNA fragmentation factor (DFF) is involved in the caspase-3 apoptotic pathway. DFF is composed of two subunits, a 45 kDa subunit called DFF-45 (also designated ICAD, for inhibitor of CAD), and CPAN (caspase-activated nuclease), also designated CAD (caspase-activated deoxyribonuclease). CPAN is a DNase that is responsible for DNA degradation during apoptosis. CPAN is inhibited by DFF-45. Caspase-3 acts to dissociate CPAN from DFF-45, allowing CPAN to enter the nucleus and degrade DNA. CIDE-A and CIDE-B have been identified as proteins that share homology with the N-terminal region of DFF-45. Like CPAN, CIDE-A and CIDE-B promote cell death and DNA fragmentation and are inhibited by DFF-45.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CIDEB polyclonal antibody detects endogenous levels of CIDEB protein.

BiowMW :~ 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cell death activator CIDE-B; Cell death-inducing DFFA-like effector B

Immunogen :Synthetic peptide, corresponding to amino acids 104-148 of Human CIDEB

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CIDEB polyclonal antibody at 1:500 dilution Lane1:L02 whole cell lysate(40ug) Lane2:SK-OVCAR3 whole cell lysate(40ug) Lane3:The Spleen lysate of Mouse(40ug) Lane4:The Spleen lysate of Rat(40ug)