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ZMYND8 polyclonal antibody

货号: BS61552

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61552

Product Name :ZMYND8 polyclonal antibody

Swiss-Prot :Q9ULU4

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. Receptor for activated C kinases, termed RACKs, are intracellular receptors for activated PKC that serve as anchors and may be involved in the activation-induced translocation of PKC. RACK7 (receptor for activated C kinase 7), also known as ZMYND8 (zinc finger MYND domain-containing protein 8), PRKCBP1 (protein kinase C (PKC)-binding protein 1) or PRO2893, is a widely expressed protein with predominant expression in pancreas, lung, placenta and brain. RACK7 contains one bromodomain, one PHD-type zinc finger, one MYND-type zinc finger and one PWWP domain. Via its C-terminus, RACK7 interacts with PKC ∫ and is believed to play a role in PKC signaling and function as a transcription regulator. In response to DNA damage, RACK7 is phosphorylated by ATM or ATR. In addition, multiple isoforms exist for RACK7.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ZMYND8 polyclonal antibody detects endogenous levels of ZMYND8 protein.

BiowMW :~ 190 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein kinase C-binding protein 1; Cutaneous T-cell lymphoma-associated antigen se14-3; Rack7; Zinc finger MYND domain-containing protein 8

Immunogen :Synthetic peptide, corresponding to amino acids 586-630 of Human ZMYND8

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ZMYND8 polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:Panc1 whole cell lysate(40ug)