中国 EN 400-660-9091

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

TRPS1 polyclonal antibody

货号: BS61549
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS61549
Product Name :TRPS1 polyclonal antibody
Swiss-Prot :Q9UHF7
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB
Application_all :WB: 1:500~1:1000
Background :The autosomal dominant tricho-rhino-phalangeal syndrome type 1 (TRPS1) is a rare disorder clinically characterized by sparse scalp hair, a bulbous nose, protruding ears, a thin upper lip, an elongated philtrum and bone deformities. The human TRPS1 gene maps to chromosome 8q24 and encodes a GATA-type zinc-finger protein. TRPS1 binds GATA sequences but does not activate GATA-dependent transcription. In fact, TRPS1 represses transcriptional activation mediated by other GATA factors. The noncompetitive mechanism for transcriptional repression depends upon an Ikaros-like C-terminal region. In mice, mutations in the GATA domain of TRPS1 cause facial abnormalities that parallel TRPS1 symptoms. TRPS1 is expressed during mouse embryonic development in developing joints, hair follicles, snout, lung, spine and brain.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :TRPS1 polyclonal antibody detects endogenous levels of TRPS1 protein.
BiowMW :~ 141 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Zinc finger transcription factor Trps1; Tricho-rhino-phalangeal syndrome type I protein; Zinc finger protein GC79
Immunogen :Synthetic peptide, corresponding to amino acids 137-181 of Human TRPS1
Conjugate :Unconjugated
Modification :Unmodification
Western blot (WB) analysis of TRPS1 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:PC3 whole cell lysate(40ug) Lane3:The fetal Brain tissue lysate of Mouse(40ug) Lane4:The fetal Brain tissue lysate of Rat(40ug)

关注我们

400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com