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MRPL48 polyclonal antibody

货号: BS61536

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS61536

Product Name :MRPL48 polyclonal antibody

Swiss-Prot :Q96GC5

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L48 (mitochondrial ribosomal protein L48), also known as HSPC290, is a 212 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-L48 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MRPL48 polyclonal antibody detects endogenous levels of MRPL48 protein.

BiowMW :~ 23 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :39S ribosomal protein L48, mitochondrial; L48mt; MRP-L48

Immunogen :Synthetic peptide, corresponding to amino acids 164-208 of Human MRPL48.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MRPL48 polyclonal antibody at 1:500 dilution Lane1:THP-1 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:AML-12 whole cell lysate(40ug)