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NCAM1 polyclonal antibody

货号: BS61516

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61516

Product Name :NCAM1 polyclonal antibody

Swiss-Prot :P13591

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains . NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma . CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 also express CD56 .

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NCAM1 polyclonal antibody detects endogenous levels of NCAM1 protein.

BiowMW :~ 120-160 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Neuronal and Glial Cell Marker Atlas,Tumor-Infiltrating Immune Cell Marker Guide,

Alternative Name :Neural cell adhesion molecule 1; N-CAM-1; NCAM-1; CD56

Immunogen :Synthetic peptide, corresponding to amino acids 262-306 of Human NCAM1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of NCAM1 polyclonal antibody at 1:500 dilution Lane1:HCT116 whole cell lysate(30ug) Lane2:MCF-7 whole cell lysate(30ug) Lane3:L02 whole cell lysate(30ug) Lane4:The brain tissue lysate of Mouse(40ug) Lane5:C6 whole cell lysate(40ug)