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TSSK6 polyclonal antibody

货号: BS61496

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61496

Product Name :TSSK6 polyclonal antibody

Swiss-Prot :Q9BXA6

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TSSK6 polyclonal antibody detects endogenous levels of TSSK6 protein.

BiowMW :~ 30 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK-6; Testis-specific kinase 6; Cancer/testis antigen 72; CT72; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase; TSSK6; FKSG82

Immunogen :Synthetic peptide, corresponding to amino acids 110-155 of Human TSSK6A.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TSSK6 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:The Testis tissue lysate of Rat(40ug) Lane3:The Testis tissue lysate of Mouse(40ug)