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VGLL2 polyclonal antibody

货号: BS61467

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61467

Product Name :VGLL2 polyclonal antibody

Swiss-Prot :Q8N8G2

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Vgl-2 (Transcription cofactor vestigial-like protein 2), also known as VITO-1, is a 317 amino acid protein that contains a domain through which it interacts with TEF-1, a protein that plays a role in controlling the expression of numerous genes. Specific to skeletal muscle, Vgl-2 is expressed highly in adult fast muscle and is expressed at lower levels in adult slow muscle and fetal skeletal muscle. During muscle differentiation, Vgl-2 mRNA levels increase and Vgl-2 translocates from the cytoplasm to the nucleus.Overexpression of Vgl-2 in MYOD-transfected 10T1/2 mouse embryonic fibroblasts increases expression of myosin heavy chain (MHC), which is a marker of terminal muscle differentiation. This evidence suggests that Vgl-2 is essential for muscle gene expression. There are two isoforms of Vgl-2 that are produced as a result of alternative splicing events.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :VGLL2 polyclonal antibody detects endogenous levels of VGLL2 protein.

BiowMW :~ 33 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Transcription cofactor vestigial-like protein 2; Vgl-2; Protein VITO1; VGLL2; VITO1

Immunogen :Synthetic peptide, corresponding to amino acids 34-79 of Human VGLL2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of VGLL2 polyclonal antibody at 1:500 dilution Lane1:The Heart tissue lysate of Rat(40ug) Lane2:The Heart tissue lysate of Mouse(40ug) Lane3:Hela whole cell lysate(40ug)