产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

TAGAP polyclonal antibody

货号: BS61462

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61462

Product Name :TAGAP polyclonal antibody

Swiss-Prot :Q8N103

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :TAGAP (T-cell activation Rho GTPase-activating protein) is a 731 amino acid protein that contains one Rho-GAP domain and exists as 4 alternatively spliced isoforms. TAGAP mayfunction as a GTPase-activating protein and may play important roles during T-cell activation. The gene that encodes TAGAP contains approximately 10,685 bases andmapsto human chromosome 6q25.3. Making up nearly 6% of the human genome,chromosome 6 contains around 1,200 geneswithin 170million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is as sociatedwith early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is as sociated with chromosome 6 through the HFE gene. Notably, the PARK2 gene, which is associated with Parkinson’s disease, and the genes encoding the major histocompatiblity complex proteins, are also located on chromosome 6. In addition, Stickler syndrome, hydroxylase deficiency andmaple syrup urine disease are associated with genes on chromosome 6, while a bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TAGAP polyclonal antibody detects endogenous levels of TAGAP protein.

BiowMW :~ 82 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :T-cell activation Rho GTPase-activating protein; T-cell activation GTPase-activating protein; TAGAP; TAGAP1; FKSG15

Immunogen :Synthetic peptide, corresponding to amino acids 186-231 of Human TAGAP.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TAGAP polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:RAW264.7 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug) Lane5:H9C2 whole cell lysate(40ug)