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KANK2 polyclonal antibody

货号: BS61445

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61445

Product Name :KANK2 polyclonal antibody

Swiss-Prot :Q63ZY3

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :KANK2 polyclonal antibody detects endogenous levels of KANK2 protein.

BiowMW :~ 117 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KN motif and ankyrin repeat domain-containing protein 2; Ankyrin repeat domain-containing protein 25; Matrix-remodeling-associated protein 3; SRC-1-interacting protein; SIP; SRC-interacting protein; SRC1-interacting protein; KANK2; ANKRD25; KIAA1518; MXRA3; SIP

Immunogen :Synthetic peptide, corresponding to amino acids 340-385 of Human KANK2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of KANK2 polyclonal antibody at 1:1000 dilution Lane1:HELA whole cell lysate (51.3μg) Lane2:The Uterus tissue lysate of Rat (43.4μg) Lane3:The Uterus tissue lysate of Mouse (37.4μg) Lane4:The Heart tissue lysate of Rat (43.4μg) Lane5:The Heart tissue lysate of Mouse (37.4μg)