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TNS3 polyclonal antibody

货号: BS61397

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61397

Product Name :TNS3 polyclonal antibody

Swiss-Prot :Q68CZ2

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The Tensin (Tns) family of proteins is involved in the maintenance of cellular structure by anchoring actin filaments at the focal adhesion via F-actin binding and capping activities. Tns proteins also contain a Src homology 2 (SH2) domain and have the ability to be phosphorylated, suggesting a role in signal transduction cascades. These diverse characteristics indicate that Tns proteins may be important links between the cytoskeleton and signal transduction pathways. Tns3, also known as TEM6 or TENS1, localizes to the focal adhesions of the plasma membrane. It is predominantly expressed in thyroid and placenta but can also be found in heart, liver, brain, prostate, pancreas, kidney, lung, skeletal muscle and white blood cells. Tns3 is essential for proper growth and development, as suggested by growth retardation and death in a number of Tns3-/- mice.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TNS3 polyclonal antibody detects endogenous levels of TNS3 protein.

BiowMW :~ 155 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Tensin-3; Tensin-like SH2 domain-containing protein 1; Tumor endothelial marker 6; TNS3

Immunogen :Synthetic peptide, corresponding to amino acids 535-580 of Human TNS3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TNS3 polyclonal antibody at 1:500 dilution Lane1:H9C2 whole cell lysate(40ug) Lane2:NIH-3T3 whole cell lysate(40ug) Lane3:DLD whole cell lysate(40ug)