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TEAD2 polyclonal antibody

货号: BS61393
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS61393
Product Name :TEAD2 polyclonal antibody
Swiss-Prot :Q15562
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB
Application_all :WB:1:500~1:1000
Background :The transcriptional enhancer factor (TEF)/TEAD family includes TEF-1, TEF-3, TEF-4 and TEF-5. These proteins share a highly conserved 68-amino acid TEA/ATTS DNA-binding domain, which binds to SV40 GT-IIC (GGAATG), SphI (AGTATG), SphII (AGCATG), and muscle-specific M-CAT (GGTATG) enhansons. TEFs are differentially expressed in human cultured cell lines and mouse embryonic and extra-embryonic tissues. Specifically, TEF-4 is strongly coexpressed with TEF-1 in mouse mitotic neuroblasts and is also detected in the gut and the nephrogenic region of the kidney. TEF-4 associates with the powerful transcriptional coactivator YAP65 to mediate mitogenic signals. In addition, TEF-4 promotes the activation of the CTP:phosphocholine cytidylyltransferase (CCT) alpha protein, which is the rate-limiting enzyme of phosphatidylcholine biosynthesis, by enhancing the transcriptional activity of Ets-1.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :TEAD2 polyclonal antibody detects endogenous levels of TEAD2 protein.
BiowMW :~ 49 kDa
Note :For research use only, not for use in diagnostic procedure.
Pathway :hippo Signaling,
Alternative Name :Transcriptional enhancer factor TEF-4; TEA domain family member 2; TEAD-2; TEAD2; TEF4
Immunogen :Synthetic peptide, corresponding to amino acids 61-106 of Human TEAD2.
Conjugate :Unconjugated
Modification :Unmodification
Western blot (WB) analysis of TEAD2 polyclonal antibody at 1:500 dilution Lane1:HEH293T whole cell lysate(40ug) Lane2:RAW264.7 whole cell lysat(40ug) Lane3:H9C2 whole cell lysate(40ug)

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com