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TNFAIP6 polyclonal antibody

货号: BS61291
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS61291
Product Name :TNFAIP6 polyclonal antibody
Swiss-Prot :P98066
Host :Rabbit
Reactivity :Human,Rat
Applications :WB
Application_all :WB: 1:500~1:1000
Background :The TSG6 gene is transcribed in normal fibroblasts and activated by binding of the cytokines TNFα and IL-1 at AP-1 and NF-IL6 sites in its promoter. TSG-6 is a glycoprotein and a member of the hyaluronan-binding protein family, which includes cartilage link protein, proteoglycan core protein and the adhesion receptor CD44. TSG-6 is highly homologous to CD44, particularly in the hyaluronic acid-binding domain. TSG-6 is found in TNF-treated cells; its expression is rapidly activated by TNFα, IL-1 and lipopolysaccharide in normal fibroblasts, peripheral blood mononuclear cells, synovial cells and chondrocytes. The presence of TSG-6 in synovial fluid suggests a possible role in rheumatoid arthritis. TSG-6 forms a stable complex with components of the serine protease inhibitor, inter-α-inhibitor (IαI). TSG-6 potentiates the inhibitory effect of lαl on the protease activity of plasmin. Through their cooperative inhibitory effect on plasmin, TSG-6 and lαl can modulate the protease network and thus inhibit inflammation.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :TNFAIP6 polyclonal antibody detects endogenous levels of TNFAIP6 protein.
BiowMW :~ 31 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Tumor necrosis factor-inducible gene 6 protein; Hyaluronate-binding protein; TNF-stimulated gene 6 protein; TSG-6; Tumor necrosis factor alpha-induced protein 6; TNF alpha-induced protein 6; TNFAIP6; TSG6
Immunogen :A synthetic peptide corresponding to residues in Human TNFAIP6.
Conjugate :Unconjugated
Modification :Unmodification
Western blot (WB) analysis of TNFAIP6 polyclonal antibody at 1:500 dilution Lane1:293T whole cell lysate Lane2:RAW264.7 whole cell lysate

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com