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ALDOC polyclonal antibody（KU）

货号: BS61191

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61191

Product Name :ALDOC polyclonal antibody（KU）

Swiss-Prot :P09972

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. Fructose 1,6-bisphosphate aldolase exists as three forms, the muscle-specific Aldolase A, the liver-specific aldolase B, and the brain-specific aldolase C. Aldolase A, B, and C arose from a common ancestral gene, from which aldolase B first diverged. Aldolase A is one of the most highly conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ALDOC polyclonal antibody detects endogenous levels of ALDOC protein.

BiowMW :~ 39 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Fructose-bisphosphate aldolase C (EC:4.1.2.13); Brain-type aldolase; ALDOC; ALDC

Immunogen :A synthetic peptide corresponding to residues in Human ALDOC.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Aldolase C (F94) pAb at 1:500 dilution Lane1:HCT116 whole cell lysate(40ug) Lane2:The Brain tissue lysate of Mouse(10ug) Lane3:The Testis tissue lysate of Rat(40ug) Lane4:K562 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of ALDOC pAb in paraffin-embedded human colon carcinoma tissue at 1:50,showing cytoplasm staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.