产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

IRF-4 polyclonal antibody

货号: BS6104

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6104

Product Name :IRF-4 polyclonal antibody

Swiss-Prot :Q15306

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IF

Application_all :WB: 1:500~1:2000 IF: 1:50~1:200

Background :Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IRF4 polyclonal antibody detects endogenous levels of IRF4 protein.

BiowMW :~ 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interferon regulatory factor 4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5; IRF4; MUM1

Immunogen :Recombinant full length Human IRF-4.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of IRF4 polyclonal antibody in extracts from HuT-78 cells and mouse lung tissue.

Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization

JournalBiochemical Pharmacology

ApplicationICC,WB

IF4.825

SpeciesMouse

PMID29753749