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Integrin β2 polyclonal antibody

货号: BS60894

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60894

Product Name :Integrin β2 polyclonal antibody

Swiss-Prot :P05107

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The small inducible genes (SIG) family encodes proteins that are involved in overlapping processes of inflammation, immune response, wound repair and coagulation. The SIG family contains two branches, designated CXC and CC, distinguished by whether or not the first two of four conserved cysteine residues are separated by an additional amino acid residue. The CXC SIGs map to human chromosome 4, including those encoding beta-thromboglobulin and platelet factor 4 (PF4), which are both expressed by megakaryocytes in a tissue-specific fashion and duplicated, there being a PF4 and a PF4alt gene, and a beta TG1 and beta TG2 gene. PPBPL1 (pro-platelet basic protein-like 1), also known as TGB2 (thromboglobulin, beta-2), belongs to the SIG family and is a CXC SIG protein, which contains four cysteine residues separated by a single amino acid residue. PPBPL1 is closely linked to other PPBPs, PF4s and several other CXC SIGs in a 700-kb Sfi1 fragment that localizes to chromosome 4q12-q13.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ITGB2 polyclonal antibody detects endogenous levels of ITGB2 protein.

BiowMW :~ 95 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Actin Dynamics,

Alternative Name :Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit bet; Complement receptor C3 subunit beta; CD18; ITGB2; CD18; MFI7

Immunogen :A synthetic peptide corresponding to residues in Human ITGB2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ITGB2 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate