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ZNF462 polyclonal antibody

货号: BS60800

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60800

Product Name :ZNF462 polyclonal antibody

Swiss-Prot :Q96JM2

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1,thereby recruiting histone modifying proteins. ZNF462 (zinc finger protein 462) is a 2,506 amino acid protein that localizes to nucleus and is subject to posttranslational phosphorylation upon DNA damage, possibly by ATM or ATR.Containing twenty-seven C2H2-type zinc finger motifs and existing as multiple alternatively spliced isoforms, ZNF462 is encoded by a gene located on human chromosome 9q31.2. Chromosome 9 consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects,and Familial dysautonomia, are both associated with chromosome 9.Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ZNF462 polyclonal antibody detects endogenous levels of ZNF462 protein.

BiowMW :~ 285 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Zinc finger protein 462; ZNF462; KIAA1803

Immunogen :A synthetic peptide corresponding to residues in Human ZNF462.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ZNF462 polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate Lane2:PC12 whole cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）