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CHD2 polyclonal antibody

货号: BS60787

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS60787

Product Name :CHD2 polyclonal antibody

Swiss-Prot :O14647

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains.CHD proteins alter gene expression by modifying chromatin structure,thereby altering access of the transcriptional machinery to its chromosomal DNA template. Chromodomain helicase DNA binding protein 2, also known as CHD2, is a member of the SNF2/RAD54 helicase family of chromatin remodeling and DNA-binding proteins (CDH proteins). Consisting of 1,828 amino acids, CHD2 is expressed in the nucleus and contains two chromo domains, a helicase ATP-binding domain and a helicase C-terminal domain.CHD2 is suggested to play a critical role in development, hematopoiesis and tumor suppression. Mutations in the gene encoding CHD2 may be the cause of glomerulopathy, proteinuria and significantly impaired kidney function.CHD2 exists as two alternatively spliced isoforms.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CHD2 polyclonal antibody detects endogenous levels of CHD2 protein.

BiowMW :~ 211 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :ATP-Dependent Chromatin Remodeling Complexes,

Alternative Name :Chromodomain-helicase-DNA-binding protein 2; CHD-2; ATP-dependent helicase CHD2; CHD2

Immunogen :A synthetic peptide corresponding to residues in Human CHD2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CHD2 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:A549 whole cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）