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CDC42BPA polyclonal antibody

货号: BS60785

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60785

Product Name :CDC42BPA polyclonal antibody

Swiss-Prot :Q5VT25

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues . Myotonic dystrophy kinase-related Cdc42-binding (DMPK-like) kinases-a and b (MRCK-a, b) contain a cysteine-rich motif and a putative pleckstrin homology domain . MRCKs can phosphorylate nonmuscle myosin light chain and influences actin-myosin contractility . MRCK-a can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/cofilin and to Actin cytoskeletal reorganization . MRCK-a can also influence neurite outgrowth promoted by Cdc42 and Rac .

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CDC42BPA polyclonal antibody detects endogenous levels of CDC42BPA protein.

BiowMW :~ 186kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Serine/threonine-protein kinase MRCK alpha; CDC42-binding protein kinase alpha; DMPK-like alpha; Myotonic dystrophy kinase-related CDC42-binding kinase alpha; MRCK alpha; Myotonic dystrophy protein kinase-like alpha; CDC42BPA; KIAA0451

Immunogen :A synthetic peptide corresponding to residues in Human CDC42BPA.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CDC42BPA pAb at 1:500 dilution Lane1:Panc1 whole cell lysate(40ug) Lane2: U-87MG whole cell lysate(40ug)